2-Chloro-4-(methoxycarbonyl)benzoic acid is an organic compound whose chemical formula is C9H7ClO4. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Chloro-4-(methoxycarbonyl)benzoic acid is a white crystalline solid.
-Melting point: about 147-149°C.
-Soluble: It is soluble in common organic solvents such as methanol, ethanol and dichloromethane.
Use:
-Chemical synthesis: 2-Chloro-4-(methoxycarbonyl)benzoic acid can be used as raw materials and intermediates in organic synthesis.
-Pharmaceutical field: The compound also has some applications in pharmaceutical research.
Preparation Method:
- 2-Chloro-4-(methoxycarbonyl)benzoic acid can be prepared by a variety of methods. A common method is obtained by reacting 2-chloro-4-carboxybenzoic anhydride with methoxy lithium in the presence of sodium chloride. After completion of the reaction, the product is extracted from the reaction mixture by acidification and crystallized in a suitable solvent to obtain the desired product.
Safety Information:
2-Chloro-4-(methoxycarbonyl)benzoic acid may cause irritation to the skin, eyes and respiratory system under normal operating conditions.
-During operation, appropriate personal protective equipment should be selected, such as chemical goggles, protective gloves and protective masks.
-When using or handling this compound, correct laboratory operating instructions and disposal procedures must be followed.
-During storage and transportation, it should be stored in a dry, cool, and well-ventilated place.